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KMID : 0359020080360020112
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Korean Journal of Gastrointestinal Endoscopy
2008 Volume.36 No. 2 p.112 ~ p.116
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A Case of Toxic Megacolon Associated with Fulminant Pseudomembranous Colitis
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Koh Dong-Hee
Lee Hang-Lak
Kim Jung-Mi
Moon Won
Lee Oh-Young
Yoon Byung-Chul
Choi Ho-Soon
Hahm Joon-Soo
Park Chan-Kum
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Abstract
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The clinical presentation of Clostridium difficile infection ranges from asymptomatic carriage, colitis with or without pseudomembranes, to fulminant colitis. Although not common, fulminant Clostridium difficile colitis can result in bowel perforation and peritonitis with a high mortality rate. We report a case of toxic megacolon associated with fulminant pseudomembranous colitis. We experienced a case of a 65-year-old male patient who presented with abdominal distension and pain for three days during treatment of pneumonia. We were able to diagnose the case as a toxic megacolon associated with fulminant pseudomembranous colitis. In spite of oral metronidazole treatment and conservative treatment, the clinical course worsened and the patient went into septic shock. The patient underwent a total colectomy but the clinical situation did not improve and the patient died. (Korean J Gastrointest Endosc 2008;36:112-116)
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KEYWORD
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Toxic megacolon, Clostridium difficile, Pseudomembraneous colitiss
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